PythonCollider is a Python client interface for the SuperCollider sound synthesis server.

Example:
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from pythoncollider import ugen

oscA = ugen.SinOsc(freq=3, mul=200)
oscB = ugen.SinOsc(freq=(oscA + 400))
oscB.play_now()

while 1: pass

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To use PythonCollider you'll need to have the SuperCollider application installed. It is freely available at:
http://supercollider.sourceforge.net/